Keywords : Experimental infection
ٍStudy of the effect of Cyperus rotundus acqueous extract in histopathological changes resulted by experimental infection with Echinococcus granulosus in mice
JOURNAL OF EDUCATION AND SCIENCE,
2010, Volume 23, Issue 1, Pages 50-61
This study conducted to explore the effect of Cyperus rotundus L. on growth and development of protoscolces in the liver tissue of swiss white mices infected with protoscolces of Echinococcus granulosus collected from hydatid cysts of sheep.
Study include four groups (n = 10 each) 1 st group considered control negative, 2nd control positive (infected with protoscolces only) 3rd & 4th group treated with Cyperus rotundus L. dose (0.5 mg / kg body weight) + protoscolces of Echinococcus granulosus.
Results of this study showed presence of histopathological changes in liver tissue represented by granuloma with presence of structureless hydatid cysts in some sections, on the other hand sever fatty changes, vacuoler degeneration focci, cuffening of mononuclear inflammatory cells, focal area of coagulative necrosis in addition to hemosiderine & bilirubine pigmentation have been seen.