Synthesis some of heterocyclic compounds derived from thymol
JOURNAL OF EDUCATION AND SCIENCE,
2018, Volume 27, Issue 4, Pages 46-53
AbstractA series of some hydrazones derivatives (3-7) have been synthesized from the reaction of hydrazide (2) with substituted benzaldehyde. While oxazridine derivatives (8-12) were synthesized by oxidation with hydrazones derivatives (3-7) with m-chloro per benzoic acid, the of these compounds (8-12) with ammonium thiocyanate afforded compounds (13-17). While the reaction of compound (2) with indole-2,3-dione afforded compound (18) while in reaction with mercaptoacetic acid gave Spiro indoline-2,3-thizolidine derivatives (19) when the compound allowed to react with conc., sulfuric acid and phosphoric pent oxide afford (20) and (21) respectively.
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