Effect of Ascorbic acid on the sensitivity of Salmonella typhi to antibiotics
JOURNAL OF EDUCATION AND SCIENCE,
2019, Volume 28, Issue 2, Pages 113-121
AbstractThis study included the investigation of the effect of Ascorbic acid (Vitamin C) and incubation at temperature of 44 C° on the sensitivity of Salmonella typhi to some antibiotics to which resistant it was Resistant Results showed that Ascorbic acid had a curing impact in removal of resistance character against many antibiotics (Amikacin Erythromycin ,Tobramycin, Penicillin ). Concentration of Ascorbic acid had a role in its effectiveness and the concentration (1.5) mM was the best in all curing results. The study also demonstrated that the temperature 44c° had a curing effect on the resistance of bacteria under to most studied antibiotics except erythromycin according to this results and because Ascorbic acid is not toxic, it be used with antibiotics against infection with Salmonella typhi .
1- Al-Khayat, K.H., M.Sc. Thesis, College of Education, University of Mosul (2008). (In Arabic).
2- AL-Sabauy B. D. H. M.Sc. Thesis, College of Science, University of Mosul (2005). (In Arabic).
3- Farnoosh, A. and Azam H. J Ind Microbiol Biotechnol 33: 238–242, (2006).
4- Habeb, Z.S. and Al-Shawi, A.M. Iraqi Medical Journal, Vol. 33, No. (2), (2009).
5-Ahmed, K.D. and Aziz, Z.A. Journal of Rafidain Science, Vol. (1), Issue (9). (2006).
6- Bailey, W. R. and Scott, E. G. "Diagnostic microbiology a textbook for the isolation and identification of pathologenic microorganisms". The C. V. Mosby Company. London (1974).
7- Buchanan, R. E. and Gibbons, N. E. "Bergeys manual of Determinative Bacteriology" 8th ed. Williams and Wilkins Company Baltimore (1974).
8- Toledo, I.; Cruz-Vara, L.R.; Sanchez, J.H. and Guarneros, G., J. Bacteria., 182 (6): 1523-1528, (2000).
9- Bauer, A., Kirby, W.A., Sherris, J.S., and Turk, M., Am. J. Clin. Pathol., Vol. 45: pp.493-496, (1969).
10- Vandepitte, j., Engbac, K., pito, p. and Heuch, C. C. "Basic Laboratory procedures in Clinical Bacteriology". World Health Organization. Geneva (1991).
11- Hasan, A.H., Journal of Rafidain Science, Vol. (15), Issue (5). (2004).
12- Essa, M.A.; Hamad, B.D.; Alwan, N.J., Journal of Education and Science Volume (24) Issue (3), (2011).
13- Gomez-luz, R. Int. Microbiol., 1:279-284, (1998).
14- Topf, J.and Faubel, S. "The Microbiology Companion". 2nd ed., National Reproduction Corporation, Michigan, USA. (1994)
15- Ramesh, A.; Halami, P.M. and Chandrashekar, A. World J. Microbiol. Biotechnol., 16 (7):695-697, (2000).
16-Amabile C.C., Muta.Res.207(3-4)107-9, (1988).
17-Luciana .; Edmar C. and Andréa M. A., Brazilian Archives of Biology and Technology.Vol.48, n. 3 : pp. 379-384, (2005).
18- Wameidh M.P., Iraqi Journal of Science.50(1)37-42, (2009).
19-Terawakie, Y.; Takayasu, H. and Akiba, T., J. Bacteriol., 94 (3): 687-690, (1967).
20- Al-Rashidy, D.N.M.A, M.Sc. Thesis, College of Education, University of Mosul (2002). (In Arabic).
21-Warren, R.; Rogolsky, M.; Wiley, B.B. and Glasgow, R.L., J.bacteriol., 118(3): 980-985, (1974).
22-Al-Khafagi, Z.M., "Biological activities of bacteria". Dar Al-Kutib for Printing and Publishing, University of Mosul (1987).
- Article View: 69
- PDF Download: 102