Estimating the Level of Some Inflammatory Cytokines in the Serum of Women Exposed to Abortion and the Relationship with Toxoplasmosis
JOURNAL OF EDUCATION AND SCIENCE,
This study includes the collection of (90) blood samples, eighty samples belongs to patients experienced to spontaneous or recurrent abortions, and the ten samples from women with normal pregnancy. The results showed a significant increase in the levels of cytokines in patients serum as their concentrations were (218.15±105.1 pg/L for IL-1β, 63.10±35.17 ng/L for TNF-α and 31.77±25.3ng/ml for IFN-g) compared to the control as it(151.0±0.76 pg/L ,34.96±0.42 ng/L and 11.15±3.49 ng/ml) for the cytokines respectively. The level of cytokines reached (352.18 pg/L,117.8 ng/L and 63.8 ng/ml) for IL-1β,TNF-α and IFN-g respectively in women infected with Toxoplasmosis compared to non-infected women (337.1 pg/L , 101.3 ng/L and 54.06 ng/ml). This indicate that toxoplasmosis has a role in the induction of immune system.
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