Abstract
Abstract the research involved a study of the relationship between Leptin, Insulin, with Diabetes Mellitus in type I and II compared to normals. The results demonstrated a significant decrease of Leptin and Insulin in serum of type I diabetic Patients in comparison to control , while a significant difference of leptin and Insulin between type I and II patients. The results also demonstrated a significant increase of leptin in serum of type II diabetic patients in comparison with that of control according to body mass index (BMI) , while a significant increase in serum blood glucose of type I and II patients in comparison to control. Correlation coefficient between Leptin, Insulin and blood glucose of diabetic patients showed that Insulin was the most variable linear relationship with Leptin in control and diabetes type I and II, also a linear relationship of blood glucose with Insulin hormone in control.