الملخص

This work involves,the preparation, new ligands 4-[N- (2,4-Dihydroxybenzylidene) imino] antipyrinyl Serine (L1) or with Theronine (L2),. from these ligands ,ten Complexes have been synthesized with metal ions Co(II) ,Ni(II) Cu(II) Zn (II) and Cd(II) in molar ratio (1:1) Metal: Ligand and these complexes have been characterized on the basis of physiochemical,investigations(1HNMR),(IR) electronicspectroscopy(U.V-Vis), molar,conductance, magnetic moment measurement, Thermal analysis (TGA), ,elemental analysis, Powder X-ray diffraction and spectral studies. Infrared data suggest that the ligands( L1) and( L2) behave as tetradentate ligands and coordinated through (N, N, O, O) as adonor,atoms sequence towards the metal ions, and they give an square planer and tetrahedral complexes, finally some of these,prepared complexes have been screened for their antibacterial activities against two classes of human pathogenic; bacteria Gram positive eg: Staphylococcus.aureus, and Gram negativebacteria including,Pseudomonas,aeruginosa, Klebsiella pneumoni and.Escherichiacoli, The performance results explain that the metal complexes have greater action more essential than the free ligand