الملخص

ABSTRACT This research included a clinical study of cytidine deaminase activity in serum, which included of seven types of cancer patients involve larynx, lung, renal, bladder, sarcoma, prostate and seminomia and Thalassemia patients as well as, diabetes patients. The result showed through (115) cases of cancer patients an increase with a significant difference (P<0.0001) of activity enzyme compared with (50) of healthy control, alsow to be found increase for enzyme activity in (50) cases of thalassemia patients by significant difference (P<0.05) compared with healthy control, while to exist decrease by significant difference (P<0.001) in (70) cases of diabetes patients for two types of disease diabetes (Insulline dependent and non insulline dependent) compared with control. In addition to study of influence age and sex for healthy and patients on cytidine deaminase activity, that to find out decrease significant in advanced in years of healthy control, where as an increase activity of enzyme in males of patients larynx and lung cancer.