الملخص

Abstract The study was conducted to investigate the levels of some antioxidants (Glutathion, Vitamin C, Vitamin E, Uric acid, Total protein and Albumin) in serum. Fifty six subjects were divided into two groups; group I involves (30) patients with periodontal disease and group II involves (26) healthy subjects (control). Group I was also subdivided into two subgroups; group IA (smokers) and group IB (nonsmokers). Analysis of the results showed that there was a significant increase in the level of total protein in patients in comparison with control group. Antioxidant levels were significants decreased in patients with control (Glutathion, Vitamin C, Vitamin E and Albumin). There was no difference in the level of uric acid between the two groups. The study also included the measurement of the levels of the investigated antioxidants in smokers and non smokers patients. The results indicated that there was no significant differences in the mean concentrations of antioxidant between smokers and non smokers except for glutathione level, where there was significant decrease in smoker in comparison with non smoker patients.